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Nevertheless, to study the modulation of this concentration under particular physiological or pathological conditions, the subtraction of GSSG is needed

The principle of using mAbs to increase IgG catabolism was also demonstrated in NHPs, when Nixon and colleagues at Dyax Corp used phage-display selected human IgG1 mAbs with high pH-independent affinity towards FcRn to reduce circulatory IgG without affecting albumin levels in NHPs [122]

If left untreated, severe vitamin B12 deficiency can lead to complications such as megaloblastic anemia, nerve damage, and neurological disorders

While extremely rare, allergic reactions to components in the IV solution can occur

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